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ELECTRON TRANSPORT COMPLEX IV
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DeCS
Descriptor
English
:
Electron Transport Complex IV
Descriptor
Spanish
:
Complejo IV de Transporte de Electrones
Descriptor
Portuguese
:
Complexo IV da Cadeia de Transporte de Elétrons
Synonyms
English
:
Cytochrome aa3
Cytochrome-c Oxidase
Cytochrome Oxidase
Tree Number:
D05.500.562.374
D08.811.600.250.687
D08.811.682.285
D12.776.157.530.450.250.875.304
D12.776.543.585.450.250.875.484
Definition
English
:
A multisubunit enzyme complex containing
CYTOCHROME A GROUP
; CYTOCHROME A3; two
copper
atoms; and 13 different
protein subunits
. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects
electrons
that are transferred from the reduced
CYTOCHROME C GROUP
and donates them to molecular
OXYGEN
, which is then reduced to
water
. The redox reaction is simultaneously coupled to the transport of
PROTONS
across the inner mitochondrial membrane.
Indexing Annotation
English
:
spell in titles &
translations
with lowercase c: cytochrome-c oxidase
Entry Combination - descr/qualif
English
:
Electron Transport Complex IV
/
deficiency
use
Cytochrome-c Oxidase Deficiency
See Related
English
:
Cytochrome-c Oxidase Deficiency
History Note
English
:
2004(1963); for SIGNAL PEPTIDE P25-SUBUNIT IV CYTOCHROME OXIDASE use CYTOCHROME C OXIDASE (NM) 1988-2001; for CYTOCHROME OXIDASE SUBUNIT III use CYTOCHROME C OXIDASE (NM) 1998-2001
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
31728
Unique Identifier:
D003576
Occurrence in VHL
:
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